Duchenne Muscular Dystrophy (DMD) is a hereditary X-linked fatal disease that affects 1 in 3500 male births. It is the most common kind of muscular dystrophy in children and leads to death in the late teens or early 20s for many patients. The mdx mouse is a model of DMD that can be used to investigate experimental therapies. Overexpression of a glycosyltransferase, CT GalNAc, in mdx mice has been demonstrated to prevent the development of muscular dystrophy. Overexpression of another glycosyltransferase, LARGE, is currently being investigated as a treatment for another group of muscular dystrophies, the dystroglycanopathies. In this study, we overexpressed LARGE in mdx mice in order to investigate its effect on the development of muscular dystrophy.

The purpose of this essay is to try to understand the relationship between the structures of modern working life and the development of burnout. By using the method of qualitative interviews we wanted to see if the Effort-Reward Imbalance Model could be applied to the data we had collected. Two questions have been highlighted in our research:        ? Is it possible to establish a relationship between the structures of modern working life and the development of burnout among the subjects interviewed?  ? Is it possible to explain the development of burnout among our interviewed subjects through the Effort-Reward Imbalance Model?    Our theoretical frames are the general theories of the modern society and the modern working life as developed by Anthony Giddens, Ulrich Beck and Zygmunt Bauman. We have also used Johannes Siegrist?s medical-sociological Effort-Reward Imbalance Model (ERI-Model).

Background: During the last decade physical activity among Swedish adolescents has decreased. Changes regarding physical fitness can also be seen, for instance the cardio respiratory capacity has decreased mainly among young men while muscular capacity has decreased in both genders. Physical inactivity and impaired physical fitness are both important health related parameters. 18-year olds have fulfilled their physical development and are physically on top of their development, it makes this group interesting to examine. Objective: The aim of this study was to investigate differences between physically active and inactive young men and women, concerning cardio-respiratory fitness, muscular fitness and balance.

In this investigation has an attempt to find out whether so called transplanting shock depends on the moving and transplanting of trees, to other conditions, or if it is due to the imbalance between the root to shoot ratio. Seventy trees of Prunus avium have been part of the investigation and these trees have been divided into four different groups depending on methods of production, untouched on the field, trees still on the field but with root pruning, trees moved and planted into Root-Control-Bag, trees moved and planted into Spring-rings. To be able to answer the question, measurements of the length of the terminal shoots and the lateral shoots and the dimension of the stem growth have been done and also has a visual judgment of the trees vitality been performed. The result shows that it is not only the move of the trees that gives them transplanting shock, but rather the loss of roots which gives an imbalance between the root and crown..

Följande studie avser att undersöka relationen mellan engagemang, belöning och välbefinnande på arbetsplatsen. Siegrist (1996) förklarar sambandet genom Effort-Reward Imbalance model (ERI), något som denna studie kombinerar med Dieners (1986) teori om subjektivt välbefinnande. 156 personer deltog i enkätstudien, där 97 var kvinnor. Enkäterna var utformade med påståenden där deltagarna fick skatta sina svar. Datan analyserades genom en multipel regressionsanalys, korrelationer och t-test.

Skillnaden i muskelstyrka mellan dominant och ickedominant ben hos fotbollspelare hartidigare studerats. Det finns inget enhälligt resultat om vilket ben som är starkast eller om detalls föreligger någon skillnad. Tidigare forskning har utfört mätningarna i sittandeutgångsposition vilket inte stämmer överens med fotbollspelares huvudsakliga aktivitet. Syftetmed uppsatsen var att, hos en grupp fotbollspelare i division ett och två, beskriva och jämföraden maximala muskelstyrkan mellan dominant och ickedominant ben. Datainsamlingenutfördes i en liggande utgångsposition då detta ger liknande muskellängdsförhållandet somvid stående.

Background: During the last decade climbing has become more popular and the numbers of climbers in Sweden have increased considerably. Most common are overuse injuries caused by the great stress and strain climbing creates on different parts of the body. Previous studies show that 75-90% of climbing injuries are localised in the upper extremity. Injuries affecting the lower extremity occur often acute and traumatic. Based on these facts and that the number of climbers constantly grows, it is more likely that the need of care from physiotherapist among climbers will increase.

The aim of this study is to investigate the discourses of widening recruitment to higher education in some political documents from the 21st century. The scientific method applied is critical discourse analysis as developed by Norman Fairclough. This implies the analyses of the actual texts, the social practice as well as the discursive practice, i.e. the conditions under which the texts are produced, distributed and consumed.The major results include four discourses: a post-modern discourse, a neoliberal economic discourse, a political discourse of multi-culturalism and a modern discourse with its roots in the 20th century?s discussions about social imbalance in recruitment to higher education.

AimThe aim of this study was to investigate if the Swedish elite soccer teams, both males and females, have preventive strategies to reduce the risk of muscular injuries in the posterior thigh.MethodA survey was created and sent by mail to all (n=28) Swedish elite soccer teams in allsvenskan (both males and females) to be answered by the head of physical exercise within each team. A pilot study regarding the survey was performed by two soccer coaches on elite level and was revised afterwards. The survey was conducted between May through July 2013. In total, 18 soccer teams participated in this survey.Results10 soccer teams did not respond to the survey, which resulted in a drop out of 36%. Preventive strategies to reduce the risk of muscular injuries in the posterior thigh existed in 16 of the teams.

Sarah Kane?s first play Blasted (1995) has often been read in a normative and biographical way by critics, authors and previous researchers. This essay makes a supplementary close reading of Blasted from gender and genealogical perspectives and utilizes theoretical works by Judith Butler, Luce Irigaray and Michel Foucault. My study makes clear that the characters different positions in language and talk create and maintain a power imbalance between them. Efforts to change and develop one?s individual position in language and talk are being made throughout the play since it is the only way to bring about a change in the social power structure.

A future expansion of wind power in the Nordic power system makes the balancing for the transmission system operator Svenska Kraftnät (SvK) more complicated. Up to the hour of delivery the balance responsible parties? (BRP) makes prognoses and plans, for consumption and production, to help maintain the balance in the electrical grid. How well this is accomplished is affected by the setup of the market design. Therefore SvK has proposed the following possible changes in market design: Increase the imbalance costsIntensify the regulation of imbalancesIncrease the temporal resolution on the different marketsPresent the prices for balancing power in real-timeModify the balancing market to simplify auction of consumption bidsA mapping over the BRPs? processes within planning and trading on the day-ahead, intra-day, and the balancing market has been performed in this thesis.

Sarah Kane?s first play Blasted (1995) has often been read in a normative and biographical way by critics, authors and previous researchers. This essay makes a supplementary close reading of Blasted from gender and genealogical perspectives and utilizes theoretical works by Judith Butler, Luce Irigaray and Michel Foucault. My study makes clear that the characters different positions in language and talk create and maintain a power imbalance between them. Efforts to change and develop one?s individual position in language and talk are being made throughout the play since it is the only way to bring about a change in the social power structure.

The social imbalance recruitment has been a current topic for years. Since much research has focused on the higher education's problems with this, this thesis aims to investigate if you are already at the high school choice were influenced by your social background. To get a further dimension to this topic, the French sociologist Bourdieus thoughts on people's possession of, what he calls cultural capital was used, and we made use of it in the sense of parental education. Through a survey conducted in four ninth grades in two municipalities with different characteristics in terms of socio-economic conditions, we asked questions about their choice to high school. What programs did they choose? What factors were important? And which person had influenced them? The results showed a pretty clear dividing line between the pupils who came from homes with strong cultural capital to those who did not in the same sense.

AbstractTitle: The effect of caffeine on performance during resistance training ?A systematic overviewAuthor: Amanda Jonsson and Erica BenderSupervisor: Mette AxelsenExaminer: Anna WinkvistProgramme: Dietician study programme, 180/240 ECTSType of paper: Examination paper, 15 hpDate: 2015-03-31Background: Products with high content of caffeine has in recent years become popular for optimizing physical performance. Caffeine affects mechanisms in our body which can be beneficial to perform better during exercise, but the theories have not yet been systematically reviewed.Objective: The purpose of this review article, is to examine the acute effect of caffeine intake before strength training on athletic performance with the outcome muscle endurance.Search strategy: A systematic literature search in databases PubMed, Scopus and Cochrane using keywords: ?Caffeine?, ?strength?, ?muscle?, "resistance training", "muscle strength", "strength training", "athletic performance", ?repetitions to failure?, ?muscular endurance? and ?endurance training?.Selection criteria: Healthy subjects, 16-50 years old, with experience in strength training. Studies with a caffeine intake > 5 mg/kg body weight, which participants performed dynamic strength exercises on a weight > 60% of their 1 RM.

Domestic violence against women is a widespread problem around the world, this study aims to investigate Swedish men?s attitudes towards this problem. To investigate this I have done a historic overview of the political attitude change and I interviewed two ethnic Swedish men and two men with a foreign background, this because to get a fair representation of our multicultural society. The results and conclusions is that the attitude haven?t changed that much over the years, it is mostly the latest decades that politicians and the medial debate have acknowledge the imbalance of power between the genders and that the patriarchy is a major factor towards this attitude.The interviewed showed that the men with foreign background had a tendency to have more traditionally attitude towards women then the Swedish men..